Advantages of Molecular PCR Testing for UTI Diagnosis in Memory Care Residents
Molecular UTI testing (PCR) offers clear benefits over traditional culture and sensitivity (C&S) testing for residents in Memory Care units of Assisted Living Facilities (ALFs). Many residents with dementia or cognitive decline have difficulty providing clean-catch urine samples, which makes it challenging to diagnose or rule out urinary tract infections (UTIs). In many cases, the only way to collect a sample is by swabbing a urine-soaked brief.
Molecular PCR testing can accurately detect infections from swab samples, just like it can from urine collected in a cup. This is important because traditional C&S testing needs a clean, uncontaminated sample with a specific urine volume, that can be hard to get from some residents. Contaminated samples are not accepted for testing causing a re-collection, delays in diagnosis and treatment.
In contrast, PCR testing looks for bacterial DNA/RNA, which allows it to detect a wider range of bacteria—even if the sample isn’t perfect. Unlike C&S, PCR testing can work with contaminated samples because it can identify and ignore the contaminant while still testing for the significant pathogens. This makes PCR testing much more reliable, allowing healthcare providers to make better decisions about treatment and preventing complications from untreated infections or using the wrong antibiotics.